Clausen A., Xu X., Bi X. and Baudry M.  Effects of the Superoxide Dismutase/Catalase Mimetic EUK-207 in a Mouse Model of Alzheimer’s Disease: Protection Against and Interruption of Progression of Amyloid and Tau Pathology and Cognitive Decline. J. Alzheimers Dis. 29: 1-26, 2012

Clausen A., Doctrow S. and Baudry M.  Prevention of cognitive deficit and brain oxidative stress with superoxide dismutase/catalase mimeytics in aged mice. Neurobiol Aging 31: 425-433, 2010

Browne S.E., Roberts L.J. II, Dennery P.A., Doctrow S.R., Beal M.F., Barlow C., and Levine R.L. Treatment with a catalytic antioxidant corrects the neurobehavioral defect in ataxia-telangiectasia mice. Free Radicals in Biology and Medicine 36: 938-42, 2004

Doctrow S.R., Huffman K. Marcus C., Tocco G., Malfroy E., Adinolfi C., Kruk H., Baker K., Lazarovich N., Mascarenhas J., and Malfroy B., Salen manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies. J. Medicinal Chemistry 45: 4549-58, 2002

Melov S., Doctrow S.R., Schneider J.A., Haberson J., Patel M., Coskun P.E., Huffman K. Wallace D.C., and Malfroy B. Lifespan extension and rescue of neurodegeneration in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase/catalase mimetics. J. Neuroscience, 21: 8348-53, 2001

Melov, S., Ravenscroft, J., Malik, S., Gill, M.S., Walker, D.W., Clayton, P.E., Wallace, D.C., Malfroy, B., Doctrow, S.R., and Lithgow, G. Extension of Caenorhabditis elegans lifespan with synthetic superoxide dismutase/catalase mimetics. Science 289: 1567-1569, 2000

Over 60 additional publications

Contact bmalfroy@mindset-rx.com for more information